Molecular Neurobiology

Department                             Bionanoscience

Principal investigator          Dimphna Meijer

E-mail address                      d.h.m.meijer@tudelft.nl

Website                                  www.dimphnameijerlab.org

 

Cell adhesion molecules at the synapse

In our research group we aim to understand how neurons form circuits. Intact neuronal circuits are at the basis of learning and memory. Damaged neuronal circuits can cause memory loss and behavioral or motor skills disorders. We use techniques from biochemistry, biophysics and cellular biology to address questions such as: How do neuronal circuits develop over time? Which molecules are important players in this process? What is the molecular basis of neuronal recognition?

Techniques

  • Molecular biology (cloning)
  • Biochemistry (protein purification)
  • Biophysics/structural biology (protein characterization, electron microscopy)

Further reading

Gogou, C., et al. (2023). BioRxiv. DOI: 10.1101/2023.10.27.564434.